Multiple sclerosis a comprehensive review for the physician assistant browning v1 joseph m sedrak m author information 1seton hall university south orange new jersey usa. Abstract multiple sclerosis ms is the commonest non traumatic disabling disease to affect young adults the incidence of ms is increasing worldwide together with the socioeconomic impact of the disease the underlying cause of ms and mechanisms behind this increase remain opaque although complex gene environment interactions almost certainly . Multiple sclerosis ms is a chronic demyelinating disease where nerve cells are stripped from their protective layers and ultimately stripping the person from his functions causing a multitude of neurological disabilities like motor dysfunctions coordination abnormalities visual difficulties loss of bladder or bowel control fatigue and or weakness and vertigo. Ferentiation tissue specific lymphocyte hom multiple sclerosis a comprehensive review introduction multiple sclerosis ms is a chronic debilitating neurodegenerative disease the basic disease process of multiple sclerosis is characterized by inflammation and then destruction of the myelin sheaths and axons in the central nervous system. Multiple sclerosis ms is a chronic demyelinating disease where nerve cells are stripped from their protective layers and ultimately stripping the person from his functions causing a multitude of neurological disabilities like motor dysfunctions coordination abnormalities visual difficulties loss of bladder or bowel control fatigue and or weakness and vertigo