R preston mason mary f walter charles a day robert f jacob pages 175 190 cox 2 blockade in cancer prevention and therapy. From the reviews this is an up to date review of the current understanding of inflammation the mechanisms by which it affects disease and the role of anti inflammatory medications pertaining to cox 2 and its inhibition . A comprehensive treatise of cox 2 inflammation and disease offers a spell binding look at the cox 2 controversy details new and exciting findings on cox 2 blockade in cancer prevention and therapy as well as the prevention of alzheimers disease and other neurodegenerative conditions. Request pdf inflammation in the pathogenesis of chronic diseases the cox 2 controversy leading experts review and discuss the evidence supporting the role of inflammation in the pathogenesis . In this book a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase 2 cox 2 inhibitors the authors provide exciting and enlightening perspectives on cox 2 and related molecular targets in the future of medicine including historical perspectives